Originally Posted by Greg C.
Maybe Maximum Overdrive?? That one takes place mostly around a truck stop tho....
stephen king did do maximum overdrive, but it dosen't have the "semi-truck follows this guy with big glasses on the highway" scenario in it.
going back to what the OP said about the truck having no driver... there was a driver, but they never showed him directly, just as as shadowy person behind the steering wheel, but i recall getting a good glimpse of him in the scene where the truck helped push/bumpstart the broken down school bus full of kids off to the side of the road.