Colleagues of mine in Calgary tour on their sport bikes yearly.
R6 / GSX-R 600 / ZX-14 / CBR1000RR / Hayabusa + I'm forgetting a few
They start in Calgary and usually end up in Phoenix, AZ or Las Vegas. They usually go for 2 weeks straight. If I recall correctly, they've been doing this for over 8 years with no real complaints other than the usual back aches and sore wrists. These are guys in their late 30s and 40s. One of them is 56 this year.